Question 3#

Which of the following concerning endometriosis is FALSE?

A) More common in infertile women
B) Etiology is inflammation-induced
C) Can involve the thoracic cavity
D) Can cause increase in serum CA-125

Correct Answer is B


Endometriosis is especially prevalent in patients suffering from chronic pelvic pain (80%) and infertility (20-50%). The pathophysiology of endometriosis is poorly understood; etiologic theories explaining dissemination of endometrial glands include retrograde menstruation, lymphatic and vascular spread of endometrial glands, and coelomic metaplasia. Endometriosis commonly involves the ovaries, pelvic peritoneal surfaces, and uterosacral ligaments. Other possible sites include the rectovaginal septum, sigmoid colon, intraperitoneal organs, retroperitoneal space, ureters, incisional scars, umbilicus, and even the thoracic cavity. Endometriosis can also cause increases in serum cancer antigen 125 (CA-125).