Cardiology>>>>>Arrythmias
Question 32#

Which of the following antiarrhythmic medications would be the best choice for treatment of a patient with atrial fibrillation (AFib) and significant renal insufficiency?

A. Propafenone
B. Sotalol
C. Dofetilide
D. Flecainide

Correct Answer is A

Comment:

Propafenone. Sotalol and dofetilide are primarily excreted by the renal route and should be used cautiously, if at all, in patients with significant renal insufficiency. Flecainide primarily undergoes hepatic elimination (approximately 70%) but has 25% renal elimination. The route of elimination for propafenone is 99% hepatic.