Urology>>>>>Prostate Cancer
Question 1#

Which of the following is TRUE regarding adenocarcinoma of the prostate?

A. Is the fourth commonest cause of male cancer death in the UK
B. Is more common in men than breast carcinoma is in women
C. Is more common in the transition zone than in the peripheral zone
D. Has never been recorded in patients with congenital 5α-reductase deficiency
E. The critical feature in the pathological diagnosis is preservation of basal cell layer

Correct Answer is D


Answer D

Prostate cancer is the second leading cause of male cancer death in the UK. The incidence of breast cancer exceeds that of prostate cancer in the UK (55,200 vs. 47,740, respectively). In total, about 75% of adenocarcinoma arise from the peripheral zone with the rest arising from the transition zone. Neither benign prostate hyperplasia (BPH) nor prostate cancer has ever been reported in patients with 5α-reductase deficiency. Absence of the basal layer distinguishes malignant from benign prostate acini.