Urology>>>>>Prostate Cancer
Question 2#

Which of the following is NOT a recognised side effect of LHRH agonists in the treatment of carcinoma of the prostate?

a. Osteoporosis
b. An initial drop in plasma testosterone
c. Gynaecomastia
d. Hot flushes
e. Erectile dysfunction

Correct Answer is B

Comment:

Answer B

The plasma testosterone initially rises (the tumour flare), so an anti-androgen, such as bicalutamide, is given for 3 days before and 3 weeks after starting an LHRH agonist. The remainder all are recorded side effects for androgen deprivation therapy, anti-androgens have similar side effects but with better preservation of potency and libido.