With regards to the mechanism of action of 5 Flurouracil (5-FU) cream for erythroplasia of Queyrat (EQ). Which of the following is TRUE?a. RNA synthesis is blocked
Topical 5 FU is structurally similar to thymine and blocks DNA synthesis by inhibiting thymidylate synthetase. In contrast Imiquimod is an imidazoquinonin tetracyclicamine which alters the immune response by possibly inducing interferon alpha.