Urology>>>>> Penile Cancer
Question 14#

A 69-year-old man presents to your clinic with the following lesion

on his glans and inner prepuce. The lesion persists despite topical steroid and antifungal creams. A biopsy is obtained and reveals undifferentiated PeIN. What is this lesion known as?

a. Bowen disease
b. Bowenoid papulosis
c. Erythroplasia of Queyrat
d. Buschke–Löwenstein (giant condyloma)
e. Paget’s disease

Correct Answer is C

Comment:

Answer C

PeIN affecting the glans penis or inner prepuce is referred to as erythroplasia of Queyrat (EQ). In comparison to Bowen disease it is when the skin of the penile shaft, rest of the genitalia or the perineum are affected. Management and treatment involve histopathological diagnosis and treatment options focus on penile-sparing procedures, including topical chemotherapy agents, WLE, glans resurfacing, laser therapy (CO2, neodymium:yttrium-aluminum-garnet [Nd:YAG], potassium titanyl phosphate [KTP]) and Moh’s micrographic surgery (not common practice in the UK). When the lesions are located solely on the foreskin, circumcision is often adequate for local control.