Cardiology>>>>>Pharmacology
Question 53#

One month ago, a 37-year-old woman with sinus infection responded well to a 14-day course of amoxicillin/clavulanate 875/125 mg twice daily. She is scheduled for a root canal in 1 week. In the past, her dentist had prescribed one dose of clindamycin 600 mg, 1 hour prior to any dental work, for endocarditis prophylaxis because of her history of mitral valve prolapse. Realizing she has not received her prescription, the patient calls the dentist’s office for an antibiotic. What prophylaxis is indicated for this patient? 

A. Amoxicillin 2 g PO 1 hour before the procedure
B. Clindamycin 600 mg PO 1 hour before the procedure
C. Azithromycin 500 mg PO 1 hour before the procedure
D. No prophylaxis recommended in this patient

Correct Answer is D

Comment:

d. No prophylaxis is recommended in this patient. The recommendations according to the 2007 Guidelines for Prevention of Infective Endocarditis no longer recommend prophylactic antibiotics prior to dental procedures for people with mitral valve prolapse, rheumatic heart disease, bicuspid valve disease, calcified aortic stenosis, or congenital heart conditions such as ventricular septal defect, atrial septal defect, and hypertrophic cardiomyopathy.