Critical Care Medicine-Gastrointestinal, Nutrition and Genitourinary Disorders>>>>>Diagnostic and Management Modalities
Question 4#

Which one of the following immunosuppressants is in the macrolide family?

A. Mycophenolate
B. Tacrolimus
C. Sirolimus
D. Cyclosporine

Correct Answer is C

Comment:

Correct Answer: C

Sirolimus is a macrolide antibiotic with potent immunosuppressant and antifungal properties. Tacrolimus and cyclosporine are calcineurin inhibitors. Mycophenolate is a nucleotide blocking agent.

Reference:

1. Suthanthiran M, Morris R, Strom T. Immunosuppressants: cellular and molecular mechanisms of action. Am J Kidney Dis. 1996;28(2):159-172.