Question 5#

When a patient with hemorrhagic shock is resuscitated using an intravenous colloid solution rather than lactated Ringer solution, all of the following statements are true EXCEPT:

A. Circulating levels of immunoglobulins are decreased
B. Colloid solutions may bind to the ionized fraction of serum calcium
C. Endogenous production of albumin is decreased
D. Extracellular fluid volume deficit is restored

Correct Answer is D


Because of higher osmotic pressure, colloid solutions draw extracellular fluid into the vascular space, increasing the extracellular fluid deficit. In addition, the ionized fraction of serum calcium is decreased, circulating levels of immunoglobulin drop, and reaction to tetanus toxoid given to the patient suffering from major trauma is decreased. Endogenous production of albumin also decreases. Colloid resuscitation is no more effective than crystalloid resuscitation, and it is more expensive.