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Question 5#

All of the following are true EXCEPT:

A) The relationship between EDP and preload is linear
B) EDP is determined by both volume and compliance of the ventricle
C) The relationship between EDP and end-diastolic volume (EDV) can be changed with pharmacologic agents
D) EDP is often used as a surrogate for EDV because it is easier to approximate in the clinical setting

Correct Answer is A

Comment:

Clinicians frequently use EDP as a surrogate for end-diastolic volume (EDV), but EDP is determined not only by volume but also by the diastolic compliance of the ventricular chamber. Ventricular compliance is altered by various pathologic conditions and pharmacologic agents. Furthermore, the relationship between EDP and true preload is not linear, but rather is exponential.