Multiple Choice Questions (MCQ)

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Category: Critical Care Medicine-Endocrine Disorders--->Endocrine Tumors
Page: 1

Question 1#Print Question

Pheochromocytomas are associated with all of the following familial disorders EXCEPT?

a. von Hippel-Lindau (VHL) syndrome
b. Multiple endocrine neoplasia type 2 (MEN2)
c. Hereditary nonpolyposis colorectal cancer (HPNCC)
d. Neurofibromatosis type 1 (NF1)

Question 2#Print Question

A 48-year-old female with family history of pheochromocytoma is undergoing laparoscopic nephrectomy for newly diagnosed renal cell carcinoma. The surgeons note an adrenal mass not previously seen on imaging, and manipulation of the kidney causes severe hypertension up to 225/135 mm Hg. The case is aborted, with the patient transferred to the intensive care unit for blood pressure management. In this scenario, which of the following biochemical testing is most recommended?

a. 24-hour urine catecholamines
b. Plasma catecholamines
c. 24-hour urine-fractionated metanephrines
d. Plasma-fractionated metanephrines

Question 3#Print Question

Which of the following is the appropriate management strategy of pheochromocytoma-associated hypertension?

a. α-adrenergic blockade only
b. β-adrenergic blockade only
c. α-adrenergic blockade first, then β-adrenergic blockade
d. β-adrenergic blockade first, then α-adrenergic blockade

Question 4#Print Question

Which of the following statements regarding neuroendocrine tumors is FALSE?

a. Tumor production of histamine and bradykinin causes vasodilation and flushing
b. Carcinoid syndrome only occurs in the presence of liver metastases
c. Carcinoid tumors may arise in lung, liver, and anywhere in the gastrointestinal tract
d. Serotonin can stimulate fibroblast and fibrogenesis causing valvular lesions

Question 5#Print Question

Which of the following diagnostic tests is most appropriate for suspected carcinoid tumor?

a. 24-hour urinary excretion of 5-hydroxyindoleacetic acid (5-HIAA)
b. 24-hour urinary excretion of serotonin
c. Plasma chromogranin A
d. Plasma serotonin

Category: Critical Care Medicine-Endocrine Disorders--->Endocrine Tumors
Page: 1 of 1