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Multiple Choice Questions (MCQ)

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Category: Hematologic and Oncologic Disorders--->RBC Disorders
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Question 1#Print Question

Which of the following statements regarding anemia in hospitalized patients is MOST correct?

A. A low serum iron, normal or low serum ferritin, and normal or high total iron-binding capacity are associated with iron-deficiency anemia
B. Blood draws for diagnostic studies is an infrequent cause of anemia in hospitalized patients
C. Microcytic anemia is commonly associated with acute blood loss
D. The reticulocyte percentage can be artificially decreased in severe anemia


Question 2#Print Question

A 57-year-old man has been in the ICU for 10 days with acute respiratory distress syndrome (ARDS) and sepsis due to pneumonia. His hemoglobin level is 7.5 g/dL.

Which of the following statements is MOST correct regarding management of his anemia associated with critical illness?

A. Use of recombinant human erythropoietin (EPO, epoetin alfa) will reduce his need for red-cell transfusion
B. Iron supplementation will reduce his need for red-cell transfusion
C. He should be transfused with red blood cells as patients with sepsis have better outcomes with a target hemoglobin >9
D. Strategies to minimize blood loss associated with phlebotomy such as use of pediatric tubes, point-of-care testing, or use of blood conservation devices can decrease blood loss and transfusion requirements


Question 3#Print Question

Which of the following statements regarding red blood cell transfusion in critically ill patients is MOST correct?

A. Transfusion of leukoreduced red blood cells (RBCs) is associated with decreased risk of ARDS in trauma patients
B. Transfusion of RBCs that have been stored for a longer period of time is associated with increased infection, organ dysfunction, and mortality
C. A liberal transfusion goal may be associated with an increased risk of nosocomial infections
D. Patients with coronary artery disease should have a transfusion threshold of hemoglobin 10 g/dL


Question 4#Print Question

A 63-year-old man is admitted to the ICU after exploratory laparotomy, superior mesenteric artery (SMA) thrombectomy, and small bowel resection. He received 2 L of crystalloid resuscitation in the operation room, and his estimated blood loss was 150 mL. He did not receive transfusion in the operating room. His:

  • white blood count is 20,000 cells/microL with 90% neutrophils
  • hemoglobin 19.1 g/dL
  • hematocrit 57%
  • platelet count 265,000 platelets/microL

Which of the following statements regarding his laboratory data is MOST correct?

A. His complete blood count (CBC) likely reflects a volume depleted state and no further workup is necessary
B. He cannot have polycythemia vera (PV) if the JAK2V617F mutation is not detected
C. If he has PV, he should be treated with aspirin alone
D. His serum EPO level should be low if he has PV


Question 5#Print Question

Which of the following statements regarding hemoglobinopathies is MOST correct?

A. Deoxygenation of sickle hemoglobin (HbS) results in polymerization that produces sickling of the red cell which is reversible
B. The alpha-thalassemias are usually caused by the deletion of one or more beta-globin genes
C. Fetal hemoglobin (HbF) increases the polymerization of HbS and promotes sickling of RBCs
D. Pulmonary embolism is the most common cause of death in βthalassemia major (TM)




Category: Hematologic and Oncologic Disorders--->RBC Disorders
Page: 1 of 1