A 54-year-old female is reviewed in the rheumatology clinic due to dry eyes and arthralgia. A diagnosis of primary Sjogren's syndrome is suspected.
Which one of the following features is least associated with this condition?
Correct Answer D:
Sjogren's syndrome: Sjogren's syndrome is an autoimmune disorder affecting exocrine glands resulting in dry mucosal surfaces. It may be primary (PSS) or secondary to rheumatoid arthritis or other connective tissue disorders, where it usually develops around 10 years after the initial onset. Sjogren's syndrome is much more common in females (ratio 9:1). There is a marked increased risk of lymphoid malignancy (40-60 fold).
Features:
Investigation:
Management:
Which one of the following statements regarding systemic lupus erythematous is true?
Correct Answer B:
Systemic lupus erythematosus:
Epidemiology:
Pathophysiology:
*It is said the incidence in black Africans is much lower than in black Americans - the reasons for this are unclear
A 45-year-old female with a history of rheumatoid arthritis presents to the Emergency Department with a two day history of a hot, painful, swollen right elbow joint.
What is the most appropriate management?
Correct Answer A: Joint aspiration is mandatory in all patients with a hot, swollen joint to rule out septic arthritis. If this was excluded in the above patient then intra-articular or system steroid therapy may be considered.
Septic arthritis: Overview:
A 45-year-old man presents with a painful swelling on the posterior aspect of his elbow. There is no history of trauma. On examination an erythematous tender swelling is noted.
What is the most likely diagnosis?
Correct Answer E:
Elbow pain: The table below details some of the characteristic features of conditions causing elbow pain:
Which one of the following features is least commonly seen in drug-induced lupus?
Correct Answer A: Glomerulonephritis is unusual in drug-induced lupus.
Drug-induced lupus: In drug-induced lupus not all the typical features of systemic lupus erythematosus are seen, with renal and nervous system involvement being unusual. It usually resolves on stopping the drug.
Causes:
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