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Multiple Choice Questions (MCQ)

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Category: Surgery--->Colon, Rectum, and Anus
Page: 7

Question 31#Print Question

A 32-year-old man presents to the ED with a 2-month history of alternating diarrhea and constipation, rectal bleeding, a 20-lb weight loss, and worsening fatigue. What are the most common genetic mutations that could have led to the development of this patient's colon cancer?

a. APC, deleted in colorectal carcinoma (DCC), p53
b. APC, BRCA1, K-ras
c. DCC, p53, and MYH gene on chromosome 6p
d. MYH gene on chromosome 1p, APC, K-ras


Question 32#Print Question

A 64-year-old man presents to the clinic with a 1 -month history of 10-lb weight loss and rectal bleeding. His hematocrit is found to be 27. On colonoscopy he is found to have a large cecal mass. What risk factors should he have modified to prevent development of colon cancer?

a. Eating a high-fat, high-protein, and low-carbohydrate diet and drinking a bottle of wine a day
b. Eating a high-fiber, low-fat, and low-protein diet, drinking a six packs of beer a day
c. Eating a high-fiber, low-fat, and high-protein diet and drinking only on holidays
d. Eating a high-fat, low-fiber diet and drinking only on holidays


Question 33#Print Question

A 63-year-old man undergoes a screening colonoscopy and is found to have a polyp in his sigmoid colon. Which type of polyp is most associated with malignancy?

a. Tubular adenoma
b. Villous adenoma
c. Tubulovillous adenoma
d. 1 cm polyp


Question 34#Print Question

A 50-year-old woman presents to the ED after having her first colonoscopy on her birthday. She endorses left lower quadrant abdominal pain and is febrile to 38.5°C. What complications after a colonoscopy require emergent laparotomy?

a. Small perforation in a stable patient
b. Hypotension and temperature of 38°C in an otherwise stable patient
c. Rigid abdomen and severe abdominal pain in a patient with poor bowel preparation
d. Findings of a large, flat sessile polyp


Question 35#Print Question

A 36-year-old woman with a complicated family history including her grandmother, mother, and sister who were diagnosed with colon cancer and a younger sister who was recently diagnosed with pancreatic cancer presents to the clinic for genetic counseling. What is a correct statement about this syndrome?

a. It is the result of mismatch repair genes such as PAP and screening criteria look for three family members who have related cancers or two family members diagnosed before age 50
b. It is the result of an autosomal dominant condition and screening criteria look for three family members with the diagnosis of adenocarcinoma or two relatives diagnosed before age 50
c. It is the result of mismatch repair genes such as PMS2 or MSH6 and three affected relatives with histologically verified adenocarcinoma of the large bowel in two successive generations of a family with one patient diagnosed before age 50
d. It is the result of an autosomal dominant condition and three affected relatives with histologically verified adenocarcinoma of the large bowel in two successive generations of a family with one patient diagnosed before age 50




Category: Surgery--->Colon, Rectum, and Anus
Page: 7 of 8